One in seven people have a genetic defect where they cannot convert folate to its final usable form. Folic acid/Folate is needed to reduce several inflammatory pathways and allergies. It is needed for detoxification, cell repair, inflammation and mood. Chronic deficiencies can lead to heart disease, Alzheimer’s, and Parkinson’s. 5-MTHF is the final usable form and will counteract this deficiency.