Vitamin B-6 is one of the vitamins I use most in my practice. Pyridoxal 5′-phosphate is the bioactive form of vitamin B6 and is what I recommend. B-6 is a water-soluble B vitamin. It is necessary for myelin (nerve cell) production, hemoglobin production, and neurotransmitter production. It helps with multiple inflammatory pathways, allergies, depression, and anxiety. It also helps with fluid retention, low back pain, PMS, carpal tunnel, and food allergies. In May, P-5-P is 20% off.