Pyridoxal 5′-Phosphate is the bioactive form of B-6. I is necessary for myelin (nerve cells), case hemoglobin and neurotransmitter production. It helps with multiple inflammatory pathways, cialis allergies, pilule depression, and anxiety. It also helps with fluid retention, low back pain, pms, carpal tunnel, and food allergies. I probably use this vitamin the most in my practice. For the month of March, P-5-P will be 20% off.